Falke Joseph J, Erbse Annette H
Structure. 2009 Sep 9;17(9):1149-51. doi: 10.1016/j.str.2009.08.005.
Previous evidence has indicated that the transmembrane signal in bacterial chemoeceptors is carried by the piston displacement of a membrane-spanning signaling helix. Hendrickson and coworkers (Cheung and Hendrickson, 2009; Moore and Hendrickson, 2009) now provide structural evidence that suggests piston transmembrane signaling is widely conserved in bacterial receptors that control ubiquitous two-component signaling pathways.
先前的证据表明,细菌化学感受器中的跨膜信号是由跨膜信号螺旋的活塞位移来传递的。亨德里克森及其同事(张和亨德里克森,2009年;摩尔和亨德里克森,2009年)现在提供的结构证据表明,活塞跨膜信号在控制普遍存在的双组分信号通路的细菌受体中广泛保守。