Ankara Universitesi Tip Fakültesi, Plastik ve Rekonstrüktif Cerrahi, Ad Cebeci Hastanesi, Dikimevi, Ankara, Turkey.
Aesthetic Plast Surg. 2010 Apr;34(2):193-9. doi: 10.1007/s00266-009-9408-y. Epub 2009 Sep 17.
The purpose of this study was to investigate the morphological, histopathological, and electrophysiological changes of peripheral nerve after CO(2) (carbon dioxide), Er:YAG (erbium:yttrium aluminum garnet), and CO(2) + Er:YAG laser irradiation. There have been no comparative reports on CO(2), Er:YAG, and CO(2) + Er:YAG laser effects on peripheral nerve.
Thirty Wistar albino rats were randomly assigned to three groups. Group I received CO(2), group II Er:YAG, and group III CO(2) + Er:YAG laser irradiation. Contralateral untreated sciatic nerves from the same animals were used as controls. The effect of laser on the peripheral nerve was assessed morphologically, histopathologically, and electrophysiologically after 6 weeks of laser irradiation.
No significant difference was observed between the treated and the untreated nerves.
The overall findings indicated that CO(2), Er:YAG, and CO(2) + Er:YAG lasers may be used safely in nerve tissue surgery.
本研究旨在探讨 CO2（二氧化碳）、Er:YAG（掺铒钇铝石榴石）和 CO2+Er:YAG 激光照射后外周神经的形态、组织病理学和电生理学变化。目前尚无关于 CO2、Er:YAG 和 CO2+Er:YAG 激光对外周神经影响的对比报告。
将 30 只 Wistar 白化大鼠随机分为三组。第 I 组接受 CO2 激光照射，第 II 组接受 Er:YAG 激光照射，第 III 组接受 CO2+Er:YAG 激光照射。来自同一动物的对侧未处理坐骨神经作为对照。激光照射 6 周后，从形态学、组织病理学和电生理学方面评估激光对周围神经的影响。
治疗组和未治疗组之间未见明显差异。
总体研究结果表明，CO2、Er:YAG 和 CO2+Er:YAG 激光可安全用于神经组织手术。
