Department of Otolaryngology/Head and Neck Surgery, VU University Medical Center, Amsterdam, The Netherlands.
Dysphagia. 2010 Sep;25(3):169-76. doi: 10.1007/s00455-009-9236-x. Epub 2009 Sep 17.
The aim of this work was to assess the efficacy of external myotomy of the upper esophageal sphincter (UES) for oropharyngeal dysphagia. In the period 1991-2006, 28 patients with longstanding dysphagia and/or aspiration problems of different etiologies underwent UES myotomy as a single surgical treatment. The main symptoms were difficulties in swallowing of a solid-food bolus, aspiration, and recurrent incidents of solid-food blockages. Pre- and postoperative manometry and videofluoroscopy were used to assess deglutition and aspiration. Outcome was defined as success in the case of complete relief or marked improvement of dysphagia and aspiration and as failure in the case of partial improvement or no improvement. Initial results showed success in 21 and failure in 7 patients. The best outcomes were observed in patients with dysphagia of unknown origin, noncancer-related iatrogenic etiology, and neuromuscular disease. No correlation was found between preoperative constrictor pharyngeal muscle activity and success rate. After follow-up of more than 1 year, 20 patients were marked as success and 3 as failure. All successful patients had full oral intake with a normal bolus consistency without clinically significant aspiration. We conclude that in select cases of oropharyngeal dysphagia success may be achieved by UES myotomy with restoration of oral intake of normal bolus consistency.
本研究旨在评估上食管括约肌(UES)外部肌切开术治疗口咽性吞咽困难的疗效。1991 年至 2006 年间,28 例不同病因的长期吞咽困难和/或吸入问题患者接受了 UES 肌切开术作为单一的手术治疗。主要症状为固体食物团块吞咽困难、吸入和反复发生固体食物堵塞。术前和术后测压和视频透视用于评估吞咽和吸入。结果定义为吞咽和吸入困难完全缓解或明显改善为成功,部分改善或无改善为失败。初步结果显示 21 例成功,7 例失败。在吞咽困难原因不明、非癌症相关医源性病因和神经肌肉疾病患者中观察到最佳结果。术前缩咽肌活动与成功率之间无相关性。随访 1 年以上后,20 例患者被标记为成功,3 例患者为失败。所有成功的患者都可以正常口服正常稠度的食物,没有明显的临床吸入。我们得出结论,在选择的口咽性吞咽困难病例中,UES 肌切开术可能会成功,恢复正常稠度的口服摄入。