McCullagh Emma, Farlow Justin, Fuller Christopher, Girard Juliet, Lipinski-Kruszka Joanna, Lu Dan, Noriega Thomas, Rollins Geoffrey, Spitzer Russell, Todhunter Michael, El-Samad Hana
TETRAD Graduate Program, University of California, San Francisco, California, USA.
Nat Chem Biol. 2009 Oct;5(10):699-704. doi: 10.1038/nchembio.222.
Phenotypic diversity exists even within isogenic populations of cells. Such nongenetic individuality may have wide implications for our understanding of many biological processes. The field of study concerned with the investigation of nongenetic individuality, also known as the 'biology of noise', is ripe with exciting scientific opportunities and challenges.
即使在同基因细胞群体中也存在表型多样性。这种非遗传个体性可能对我们理解许多生物学过程具有广泛影响。研究非遗传个体性的领域,也被称为“噪声生物学”,充满了令人兴奋的科学机遇和挑战。