Adamicová K, Fetisovavá Z, Výbohová D, Mellová Y, Chromej I
Ustav patologickej anatómie, Jesseniova lekárska fakulta v Martine, Univerzita Komenského v Bratislave.
Cesk Patol. 2009 Jul;45(3):75-8.
A 26-year-old woman suddenly noticed an onset of disseminated papular exanthema during her institutional treatment for alcohol abuse. After 9 weeks of slowly progressive course a dermatologist was consulted, who suggested a diagnosis of pityriasis lichenoides. Skin biopsy revealed cystical enlargement of hair follicles that were filled up with keratinous and parakeratotic masses interspersed with particles of fragmented collagen. Numerous inflammatory cells were present within the lesion. Many focal perforations of infundibular epithelium draining a cellular debris were prominent. Severely disturbed follicles were engulfed by giant cell inflammatory infitrate containing remnants of collagen and elastic fibers. Considering all the histopathologic findings and clinical course, the case was finally diagnosed as perforating folliculitis, a distinct type from the family of perforating dermatoses.
一名26岁女性在戒酒机构治疗期间突然出现弥漫性丘疹性皮疹。病程缓慢进展9周后咨询了皮肤科医生，医生建议诊断为苔藓样糠疹。皮肤活检显示毛囊呈囊性扩大，充满角质和不全角化物质，并夹杂着破碎的胶原颗粒。病变内有大量炎性细胞。许多漏斗状上皮的局灶性穿孔排出细胞碎片很明显。严重受损的毛囊被含有胶原和弹性纤维残余物的巨细胞炎性浸润所包绕。综合所有组织病理学表现和临床病程，该病例最终诊断为穿通性毛囊炎，这是穿通性皮肤病家族中的一种独特类型。
