Department of Dermatology, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
Eur J Dermatol. 2010 May-Jun;20(3):364-6. doi: 10.1684/ejd.2010.0924. Epub 2010 Feb 22.
Perforating folliculitis is characterized by asymptomatic skin-coloured or erythematous scattered and aggregated follicular papules with a central keratotic plug. Histologically, a superficial type can be distinguished from the profound type where perforations and rupture of the follicular wall take place at different levels of the hair follicle. This goes along with a granulomatous reaction of the entire pilary complex with destruction of the follicle epithelium and sebaceous gland. Often cases are associated with systemic disorders such as renal diseases or diabetes mellitus. We describe two patients with the profunda type of perforating folliculitis with scarring that manifested in early adulthood without any underlying disorders.
穿凿性毛囊炎的特征为无症状的肤色或红斑性、分散的、聚集的毛囊丘疹，中央有角化栓。组织学上，可将其分为浅表型和深部型，深部型在毛囊的不同水平发生穿孔和毛囊壁破裂，同时整个毛乳头复合体发生肉芽肿反应，破坏毛囊上皮和皮脂腺。此类病例常与系统性疾病相关，如肾脏疾病或糖尿病。我们描述了两例深部型穿凿性毛囊炎病例，表现为早期成年发病且无潜在疾病的瘢痕。
