Hasegawa Hirotsugu, Nakamura Yutaro, Kaida Yusuke, Enomoto Noriyuki, Hashimoto Dai, Inui Naoki, Suda Takafumi, Chida Kingo
Department of Respiratory Medicine, Hamamatsu University School of Medicine.
Nihon Kokyuki Gakkai Zasshi. 2009 Aug;47(8):698-703.
A 72-year-old-man was admitted to our hospital because of an abnormal chest shadow. Histological findings from video-assisted thoracoscopic surgical lung biopsy showed desquamative interstitial pneumonia (DIP). Although DIP is classified as the idiopathic interstitial pneumonias (IIPs), it is widely accepted that the cause of DIP might be associated with cigarette smoking. The patient had chronic hepatitis C virus (HCV) infection; however he did not have a history of active or passive smoking. An immunologic response to HCV infection may have a role in the pathogenesis of DIP in patients with chronic HCV. DIP should be included in the differential diagnosis of diffuse parenchymal lung disease in patients with HCV infection.
一名72岁男性因胸部阴影异常入住我院。电视辅助胸腔镜手术肺活检的组织学检查结果显示为脱屑性间质性肺炎(DIP)。尽管DIP被归类为特发性间质性肺炎(IIP),但人们普遍认为DIP的病因可能与吸烟有关。该患者患有慢性丙型肝炎病毒(HCV)感染;然而,他没有主动或被动吸烟史。对HCV感染的免疫反应可能在慢性HCV患者DIP的发病机制中起作用。HCV感染患者弥漫性实质性肺疾病的鉴别诊断应包括DIP。