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衰老肾脏的解剖和生理变化。

Anatomic and physiologic changes of the aging kidney.

机构信息

Division of Nephrology, University of Illinois at Chicago College of Medicine/Associates in Nephrology, SC, 3543 Wisconsin Avenue, Berwyn, IL 60402, USA.

出版信息

Clin Geriatr Med. 2009 Aug;25(3):325-9. doi: 10.1016/j.cger.2009.06.007.

Abstract

Aging is a degenerative biologic process that affects the kidneys. It is known to be associated with a decline in kidney function coincident with a progressive decrease in the number of functioning nephrons and with glomerular and tubulointerstitial scarring. These changes affect glomerular and tubular function, systemic hemodynamics, and, as a whole, body homeostasis.

摘要

衰老是影响肾脏的退行性生物过程。已知它与肾功能下降有关,同时伴随着功能肾单位数量的逐渐减少以及肾小球和肾小管间质瘢痕形成。这些变化影响肾小球和肾小管功能、全身血液动力学以及整体的体内平衡。

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