Kassiotis George, O'Garra Anne
Division of Immunoregulation, MRC National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK.
Immunity. 2009 Sep 18;31(3):450-2. doi: 10.1016/j.immuni.2009.08.017.
Among other genes, expression of the Bcl-6 transcriptional repressor distinguishes follicular helper T (Tfh) cells from other helper T cell subsets. In this issue of Immunity, Yu et al. (2009) demonstrate that Bcl-6 directs Tfh cell differentiation.
在其他基因中,Bcl-6转录抑制因子的表达可将滤泡辅助性T(Tfh)细胞与其他辅助性T细胞亚群区分开来。在本期《免疫》杂志中,Yu等人(2009年)证明Bcl-6指导Tfh细胞的分化。