Human Cortical Physiology and Stroke Neurorehabilitation Section, NINDS, NIH, Bethesda, Maryland, USA.
Neurorehabil Neural Repair. 2010 Feb;24(2):125-35. doi: 10.1177/1545968309345270. Epub 2009 Sep 18.
Motor impairments are a major cause of morbidity and disability after stroke. This article reviews evidence obtained using transcranial magnetic stimulation (TMS) that provides new insight into mechanisms of impaired motor control and disability. They briefly discuss the use of TMS in the diagnosis, prognosis, and therapy of poststroke motor disability. Particular emphasis is placed on TMS as a tool to explore mechanisms of neuroplasticity during spontaneous and treatment-induced recovery of motor function to develop more rational and clinically useful interventions for stroke rehabilitation.
运动障碍是中风后发病率和残疾的主要原因。本文综述了使用经颅磁刺激(TMS)获得的证据,这些证据为受损运动控制和残疾的机制提供了新的见解。他们简要讨论了 TMS 在中风后运动障碍的诊断、预后和治疗中的应用。特别强调了 TMS 作为一种工具,用于探索自发性和治疗诱导的运动功能恢复过程中的神经可塑性机制,以开发更合理和更具临床应用价值的中风康复干预措施。