Department of Bioscience and Buccal Diagnosis, São Jose dos Campos School of Dentistry, State University of São Paulo, São José dos Campos, Brazil.
Med Oral Patol Oral Cir Bucal. 2010 Mar 1;15(2):e407-12.
The aim of this study was to carry out an in vivo assessment of bone ingrowth in two different types of porous titanium -the first being completely porous, and the second with a porous surface and dense nucleus, manufactured by powder metallurgy- and to evaluate their mechanical properties.
Ten scaffolds from each group were submitted to metallographic analysis and compression tests. Next, two scaffolds of each type were inserted into 14 rabbits, which were sacrificed 8 weeks after surgery. The samples were submitted for histological examination.
Metallographic analysis revealed interconnected pores, and the average interconnected pore diameter was about 360 mm, with 36% total porosity. The totally porous titanium samples and the titanium samples with porous surface and dense nucleus showed an average compressive strength of 16.19 MPa and 69.27 MPa, respectively. After 8 weeks, the animals showed bone ingrowth, even into the most internal pores.
The pore morphology was effective in permitting bone ingrowth in both groups. Titanium scaffolds with a porous surface and dense nucleus showed the best mechanical properties and most adequate interface.
本研究旨在对两种不同类型的多孔钛进行体内骨植入评估，一种是完全多孔的，另一种是通过粉末冶金制造的具有多孔表面和致密核的，同时评估它们的机械性能。
每组 10 个支架进行金相分析和压缩试验。然后，每种类型的两个支架被植入 14 只兔子中，在手术后 8 周处死。对样本进行组织学检查。
金相分析显示出相互连通的孔隙，平均连通孔隙直径约为 360 毫米，总孔隙率为 36%。完全多孔钛样品和具有多孔表面和致密核的钛样品的平均抗压强度分别为 16.19 MPa 和 69.27 MPa。8 周后，动物体内出现了骨植入，甚至进入了最内部的孔隙。
两种类型的支架的孔隙形态都有效地促进了骨植入。具有多孔表面和致密核的钛支架具有最佳的机械性能和最合适的界面。
