三叉神经痛患者及对照者体内抗1型单纯疱疹病毒亚单位抗原的抗体

Antibodies against herpes simplex virus type 1 subunit antigens in patients with trigeminal neuralgia and controls.

作者信息

Marttila R J, Frey H, Kalimo K O, Rautakorpi I, Törmä T

出版信息

Acta Neurol Scand. 1977 Aug;56(2):177-80. doi: 10.1111/j.1600-0404.1977.tb01422.x.

DOI:10.1111/j.1600-0404.1977.tb01422.x

PMID:197767

Abstract

Serum IgG antibody levels against herpes simplex virus (HSV) type 1 subunit (capsid, envelope, and excreted) antigens detected with radioimmunoassay were compared in 25 patients with trigeminal neuralgia and their age- and sex-matched controls. No significant differences were found between the patients and controls, either in the distribution of the antibody titers or in the mean titers against any of the subunit antigens tested. In 6 patients HSV antibody titers were tested before and after trigeminal root section; no significant changes were observed.

摘要

采用放射免疫分析法比较了25例三叉神经痛患者及其年龄和性别匹配的对照者血清中针对1型单纯疱疹病毒（HSV）亚单位（衣壳、包膜和分泌型）抗原的IgG抗体水平。无论是抗体滴度分布还是针对任何一种检测的亚单位抗原的平均滴度，患者与对照者之间均未发现显著差异。对6例患者在三叉神经根切断术前和术后检测了HSV抗体滴度；未观察到显著变化。