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[犬莱姆病的困境,特别考虑“莱姆肾炎”]

[The dilemma with Lyme borreliosis in the dog with particular consideration of "Lyme nephritis"].

作者信息

Gerber Bernhard, Eichenberger S, Haug K, Wittenbrink M M

机构信息

Klinik für Kleintiermedizin, Vetsuise-Fakultät Universität Zürich, Zürich.

出版信息

Schweiz Arch Tierheilkd. 2009 Oct;151(10):479-83. doi: 10.1024/0036-7281.151.10.479.

Abstract

Lyme borreliosis is the most commonly reported tick-transmitted infectious disease in the northern hemisphere in humans. Certain diseases are associated with Lyme borreliosis in the dog as well, but only intermittent lameness with articular swelling, lymphadenomegaly, fever, and anorexia were experimentally documented. Lyme borreliosis is considered an over diagnosed disease. The term "Lyme nephritis" was introduced for dogs with characteristic renal lesions and typical clinical signs, in which antibodies against Borrelia burgdorferi were found. Different studies have been aimed at showing a relation between renal disease and B. burgdorferi infection; however, this was not possible until now. Reasons for the uncertainty of the effects of B. burgdorferi in the dog are the high prevalence of circulating antibodies, the unspecific clinical picture and the inaccuracy of serologic tests.

摘要

莱姆病是北半球人类中最常报告的蜱传传染病。某些疾病在犬类中也与莱姆病相关,但实验记录仅显示有关节肿胀、淋巴结肿大、发热和厌食的间歇性跛行。莱姆病被认为是一种诊断过度的疾病。“莱姆肾炎”一词用于患有特征性肾脏病变和典型临床症状且发现抗伯氏疏螺旋体抗体的犬类。不同的研究旨在表明肾脏疾病与伯氏疏螺旋体感染之间的关系;然而,到目前为止这一点尚无法做到。伯氏疏螺旋体对犬类影响存在不确定性的原因包括循环抗体的高流行率、非特异性临床表现以及血清学检测的不准确性。

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