Directorate of Research & Studies, Directorate General of Planning, Ministry of Health (HQ), Muscat, Sultanate of Oman.
Child Adolesc Psychiatry Ment Health. 2009 Sep 26;3(1):29. doi: 10.1186/1753-2000-3-29.
There is a dearth of studies exploring the magnitude of mental disorders amongst adolescents and youths in the Arab world. To our knowledge, this phase 2 survey in Oman is the first nationally representative school-based study to determine the prevalence of DSM-IV mental disorders (lifetime and over the preceding 12 months), their age-of-onset distributions and determine their severity over the past 12 months using the World Mental Health-Composite International Diagnostic Interview, the WMH-CIDI, used for international comparison.
A total of 1,682 (91.61%) students out of 1836 students who formed the phase 2 random sub-sample of a multi-stage, stratified, random sampling design (phase 1), participated in the face-to-face structured interview using the Arabic-version of WMH-CIDI 3.0.
The phase 1 results using the General Health Questionnaire (GHQ-12) and Child Depression Inventory (CDI) showed depressive symptoms to be 17% prevalent in the larger sample of 5409 adolescents and youths. Amongst the phase 2 respondents from this sample, 13.9% had at least one DSM IV diagnostic label. The lifetime prevalence of Major Depressive Disorder (MDD) was 3.0%; Bipolar Mood Disorder (BMD) was 1%, Specific phobia 5.8% and Social phobia 1.6%. The female gender was a strong predictor of a lifetime risk of MDD (OR 3.3, 95% CI 1.7-6.3, p = 0.000); Any Mood Disorders (OR 2.5, 95% CI 1.4-4.3, p = 0.002) and Specific Phobia (OR 1.5, 95% CI 1.0-2.4, p = 0.047). The severity of illness for cases diagnosed with 12 month DSM IV disorders was found to be 80% lower in females (OR 0.2, 95%CI 0.0-0.8). The estimates over the previous 12 month period when compared with the lifetime prevalence showed a 25% to 40% lower prevalence for MDD, Specific phobia, Social phobia, Any Anxiety Disorders (AAD) and Any Mood disorders (AMD) while the rate was 80% lower for Separation Anxiety Disorder/Adult Separation Anxiety (SAD/ASA). Mood disorders were significantly lower in the 14-16 age groups (70% lower) in comparison to the older age groups and AMD showed a linear increase in prevalence across increasing age groups (p = 0.035).
The implications of the present findings are not clear cut, however this study endorses the adult CIDI studies findings that mental disorders do begin earlier in life. The relatively lower prevalence of DSM IV depressive disorders cautions against any conclusive interpretation of the inflated results based on the exclusive study of the depressive symptoms alone in the same sample in the same time period. The female gender proved to be a strong predictor of lifetime risk of MDD, any mood disorder and specific phobia. Under-reporting by males or some other gender-specific factors may have contributed to such a discrepancy. The odds of the severity of illness for cases with 12 month DSM IV disorders were significantly lower in females.
在阿拉伯世界,针对青少年和青年群体的精神障碍研究相对较少。据我们所知,在阿曼进行的这项 2 期调查是首次全国代表性的基于学校的研究,旨在通过使用世界心理健康综合国际诊断访谈(WMH-CIDI)来确定 DSM-IV 精神障碍(终身和过去 12 个月)的患病率、发病年龄分布,并确定过去 12 个月的严重程度,WMH-CIDI 可用于国际比较。
共有 1836 名学生参加了多阶段、分层、随机抽样设计(第 1 阶段)的随机子样本的第 2 阶段,其中 1682 名(91.61%)学生参加了面对面的结构化访谈,使用阿拉伯语版 WMH-CIDI 3.0。
第 1 阶段使用一般健康问卷(GHQ-12)和儿童抑郁量表(CDI)的结果显示,在 5409 名青少年和青年的更大样本中,有 17%存在抑郁症状。在该样本的第 2 阶段受访者中,有 13.9%至少有一个 DSM-IV 诊断标签。终身患重度抑郁症(MDD)的患病率为 3.0%;双相情感障碍(BMD)为 1%,特定恐惧症为 5.8%,社交恐惧症为 1.6%。女性是 MDD 终生风险的强烈预测因素(OR 3.3,95%CI 1.7-6.3,p=0.000);任何心境障碍(OR 2.5,95%CI 1.4-4.3,p=0.002)和特定恐惧症(OR 1.5,95%CI 1.0-2.4,p=0.047)。对于在过去 12 个月被诊断为 DSM-IV 障碍的病例,女性的疾病严重程度低 80%(OR 0.2,95%CI 0.0-0.8)。与终身患病率相比,在过去 12 个月的估计患病率显示 MDD、特定恐惧症、社交恐惧症、任何焦虑障碍(AAD)和任何心境障碍(AMD)的患病率降低了 25%至 40%,而分离焦虑障碍/成人分离焦虑(SAD/ASA)的患病率降低了 80%。与年龄较大的年龄组相比,14-16 岁年龄组的心境障碍明显较低(低 70%),而 AMD 则显示出随着年龄组的增加,患病率呈线性增加(p=0.035)。
目前研究结果的意义尚不清楚,但本研究支持成人 CIDI 研究的发现,即精神障碍确实更早开始出现。DSM-IV 抑郁障碍的相对较低患病率告诫人们,基于同一时间同一样本中抑郁症状的单独研究得出的膨胀结果,不应得出任何结论性解释。女性是 MDD、任何心境障碍和特定恐惧症的终生风险的强烈预测因素。男性或其他特定性别因素的漏报可能导致了这种差异。患有 12 个月 DSM-IV 障碍的病例的疾病严重程度的可能性在女性中显著降低。