Department of Diabetes, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, United Kingdom.
Prim Care Diabetes. 2009 Aug;3(3):131-9. doi: 10.1016/j.pcd.2009.08.007. Epub 2009 Sep 24.
Hypoglycaemia is a frequent side-effect of treatment with insulin and sulfonylureas for people with diabetes, threatening potentially serious morbidity and preventing optimal glycaemic control. Fear of hypoglycaemia and development of syndromes such as impaired awareness and counterregulatory deficiency provide additional hazards for intensification of treatment. Rapid lowering of HbA1c may be potentially dangerous in type 2 diabetes because of the adverse cardiovascular effects induced by hypoglycaemia. Hypoglycaemia can disrupt many everyday activities such as driving, work performance and recreational pursuits. Measures to reduce the risk of hypoglycaemia are labour-intensive and require substantial resources.
低血糖是糖尿病患者使用胰岛素和磺酰脲类药物治疗的常见副作用，会威胁到潜在的严重发病率，并妨碍最佳血糖控制。对低血糖的恐惧以及诸如意识障碍和代偿不足等综合征的发展给治疗强化带来了额外的危险。由于低血糖引起的不良心血管影响，快速降低 HbA1c 在 2 型糖尿病中可能具有潜在危险。低血糖会干扰许多日常活动，如驾驶、工作表现和娱乐活动。降低低血糖风险的措施需要大量的劳动和资源。
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