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根据鹿特丹标准,多囊卵巢综合征的不同表型在类固醇生成方面存在差异,但胰岛素抵抗情况相似。

Different phenotypes of polycystic ovary syndrome by Rotterdam criteria are differently steroidogenic but similarly insulin resistant.

机构信息

Medical School, Nanjing University, Nanjing, People's Republic of China.

出版信息

Fertil Steril. 2010 Mar 1;93(4):1362-5. doi: 10.1016/j.fertnstert.2009.07.1678. Epub 2009 Sep 26.

DOI:10.1016/j.fertnstert.2009.07.1678
PMID:19782351
Abstract

In traditional Chinese medicine, polycystic ovary syndrome (PCOS) is considered an anovulation disorder related to ovarian insulin resistance. The three phenotypes of PCOS, according to the Rotterdam criteria, are differently steroidogenic but similarly insulin resistant, suggesting a similar involvement of insulin resistance/hyperinsulinemia in different compartments of the PCOS ovary, namely, overactive theca and/or granulosa cells.

摘要

在中医中,多囊卵巢综合征(PCOS)被认为是一种与卵巢胰岛素抵抗相关的无排卵障碍。根据鹿特丹标准,PCOS 的三种表型在类固醇生成方面存在差异,但胰岛素抵抗相似,这表明胰岛素抵抗/高胰岛素血症在 PCOS 卵巢的不同部位(即过度活跃的卵泡膜细胞和/或颗粒细胞)有相似的参与。

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