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变形链球菌的多个双组分系统调节精氨酸脱亚氨酶基因表达和应激耐受性。

Multiple two-component systems of Streptococcus mutans regulate agmatine deiminase gene expression and stress tolerance.

作者信息

Liu Yaling, Burne Robert A

机构信息

Department of Oral Biology, University of Florida, Gainesville, FL 32610, USA.

出版信息

J Bacteriol. 2009 Dec;191(23):7363-6. doi: 10.1128/JB.01054-09. Epub 2009 Sep 25.

DOI:10.1128/JB.01054-09
PMID:19783635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2786547/
Abstract

Induction of the agmatine deiminase system (AgDS) of Streptococcus mutans requires agmatine and is optimal at low pH. We show here that the VicRK, ComDE, and CiaRH two-component systems influence AgDS gene expression in response to acidic and thermal stresses.

摘要

变形链球菌的胍丁胺脱亚氨酶系统（AgDS）的诱导需要胍丁胺，且在低pH值时最为适宜。我们在此表明，VicRK、ComDE和CiaRH双组分系统会响应酸性和热应激影响AgDS基因的表达。

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本文引用的文献

1
Multiple two-component systems modulate alkali generation in Streptococcus gordonii in response to environmental stresses.多个双组分系统可调节戈登链球菌在应对环境压力时的碱生成。
J Bacteriol. 2009 Dec;191(23):7353-62. doi: 10.1128/JB.01053-09. Epub 2009 Sep 25.
2
AguR is required for induction of the Streptococcus mutans agmatine deiminase system by low pH and agmatine.低pH值和胍丁胺诱导变形链球菌胍丁胺脱亚氨酶系统需要AguR。
Appl Environ Microbiol. 2009 May;75(9):2629-37. doi: 10.1128/AEM.02145-08. Epub 2009 Mar 6.
3
LiaS regulates virulence factor expression in Streptococcus mutans.LiaS调节变形链球菌中毒力因子的表达。
Infect Immun. 2008 Jul;76(7):3093-9. doi: 10.1128/IAI.01627-07. Epub 2008 May 5.
4
Involvement of sensor kinases in the stress tolerance response of Streptococcus mutans.传感激酶在变形链球菌应激耐受反应中的作用
J Bacteriol. 2008 Jan;190(1):68-77. doi: 10.1128/JB.00990-07. Epub 2007 Oct 26.
5
Effects of oxygen on biofilm formation and the AtlA autolysin of Streptococcus mutans.氧气对变形链球菌生物膜形成及AtlA自溶素的影响。
J Bacteriol. 2007 Sep;189(17):6293-302. doi: 10.1128/JB.00546-07. Epub 2007 Jul 6.
6
The response regulator ComE in Streptococcus mutans functions both as a transcription activator of mutacin production and repressor of CSP biosynthesis.变形链球菌中的应答调节因子ComE既作为变链菌素产生的转录激活因子，又作为CSP生物合成的阻遏因子发挥作用。
Microbiology (Reading). 2007 Jun;153(Pt 6):1799-1807. doi: 10.1099/mic.0.2007/005975-0.
7
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