Speech and Hearing Therapy Department, Federal University of Bahia, Salvador, BA, Brazil.
Braz J Otorhinolaryngol. 2009 Jul-Aug;75(4):593-615. doi: 10.1016/s1808-8694(15)30501-2.
The vestibulocochlear nerve schwannoma (VS) is a benign tumor that stems from the edge of the Schwann s sheath. It is considered the most frequent intracranial benign tumor, of low lethality rate and unknown etiology.
to identify risk factors associated with VS.
systematic review.
electronic search of studies using the following key words: 'risk', 'schwannoma', 'vestibular', 'neuroma' and 'acoustic'. All original articles on epidemiological studies published in Portuguese, English or Spanish describing measures of association were included.
twenty case-control studies were found, most of them published in the United States. The analysis of those studies shows educational level, household income, occupation, exposure to ionizing radiation and noise, allergic diseases as well as the use of both cellular and cordless phones as risk factors for the VS.
methodological limitations and lack of precision in the findings impose limits to definitive conclusions concerning those risk factors. The current study contributes with information which can subsidize decisions related to the methodology to be used, having in mind new investigations on risk factors for VS. Therefore, it is of great help for knowledge improvement in this field.
前庭耳蜗神经鞘瘤（VS）是一种起源于施旺鞘边缘的良性肿瘤。它被认为是最常见的颅内良性肿瘤，致死率低，病因不明。
确定与 VS 相关的危险因素。
系统评价。
使用以下关键词进行电子检索研究：“风险”、“神经鞘瘤”、“前庭”、“神经瘤”和“听觉”。纳入所有描述关联度量的以葡萄牙语、英语或西班牙语发表的关于流行病学研究的原始文章。
发现了 20 项病例对照研究，其中大部分发表在美国。对这些研究的分析表明，教育程度、家庭收入、职业、电离辐射和噪声暴露、过敏疾病以及使用手机和无绳电话均为 VS 的危险因素。
方法学上的局限性和发现结果的不精确性限制了对这些危险因素的明确结论。本研究提供了有关 VS 危险因素的新信息，可为未来的研究提供参考，有助于该领域知识的提高。
