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同步辐射 X 射线小角散射成像:定量分析原理及其在研究骨整合到合成移植物材料中的应用。

Synchrotron X-ray imaging via ultra-small-angle scattering: principles of quantitative analysis and application in studying bone integration to synthetic grafting materials.

机构信息

Instituto de Física, Universidade de São Paulo, São Paulo, SP, Brazil.

出版信息

Eur Biophys J. 2010 Apr;39(5):861-5. doi: 10.1007/s00249-009-0541-y. Epub 2009 Sep 27.

DOI:10.1007/s00249-009-0541-y
PMID:19784835
Abstract

Optimized experimental conditions for extracting accurate information at subpixel length scales from analyzer-based X-ray imaging were obtained and applied to investigate bone regeneration by means of synthetic beta-TCP grafting materials in a rat calvaria model. The results showed a 30% growth in the particulate size due to bone ongrowth/ingrowth within the critical size defect over a 1-month healing period.

摘要

优化了基于分析仪的 X 射线成像中以亚像素长度尺度提取准确信息的实验条件,并将其应用于研究大鼠颅骨模型中合成 β-TCP 移植物材料的骨再生。结果表明,在 1 个月的愈合期内,由于临界尺寸缺陷内的骨长入/长入,颗粒尺寸增加了 30%。

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本文引用的文献

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Analyzer-based imaging technique in tomography of cartilage and metal implants: a study at the ESRF.基于分析仪的软骨和金属植入物断层扫描成像技术:欧洲同步辐射装置的一项研究
Eur J Radiol. 2008 Dec;68(3 Suppl):S41-8. doi: 10.1016/j.ejrad.2008.04.036. Epub 2008 Jun 26.
2
Long and compact x-ray pathway for experiments requiring high coherent x-ray beams.用于需要高相干X射线束的实验的长且紧凑的X射线光路。
Opt Express. 2008 Jun 23;16(13):9284-9. doi: 10.1364/oe.16.009284.
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X-ray imaging in advanced studies of ophthalmic diseases.
Med Phys. 2006 Jul;33(7):2338-43. doi: 10.1118/1.2207135.
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Qualitative evaluation of titanium implant integration into bone by diffraction enhanced imaging.
Phys Med Biol. 2006 Mar 7;51(5):1313-24. doi: 10.1088/0031-9155/51/5/019. Epub 2006 Feb 15.
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Multiple-image radiography for human soft tissue.用于人体软组织的多图像射线照相术。
J Anat. 2006 Jan;208(1):115-24. doi: 10.1111/j.1469-7580.2006.00502.x.
6
Tracheal respiration in insects visualized with synchrotron x-ray imaging.利用同步加速器X射线成像技术观察昆虫的气管呼吸。
Science. 2003 Jan 24;299(5606):558-60. doi: 10.1126/science.1078008.
7
Human breast cancer specimens: diffraction-enhanced imaging with histologic correlation--improved conspicuity of lesion detail compared with digital radiography.人类乳腺癌标本:衍射增强成像与组织学相关性——与数字X线摄影相比,病变细节的清晰度更高。
Radiology. 2000 Mar;214(3):895-901. doi: 10.1148/radiology.214.3.r00mr26895.
8
Calcium phosphates in oral biology and medicine.口腔生物学与医学中的磷酸钙
Monogr Oral Sci. 1991;15:1-201.