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血栓形成的透析血管通路的外科手术或血管内修复:有证据吗?

Surgical or endovascular repair of thrombosed dialysis vascular access: is there any evidence?

作者信息

Tordoir Jan H M, Bode Aron S, Peppelenbosch Noud, van der Sande Frank M, de Haan Michiel W

机构信息

Department of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.

出版信息

J Vasc Surg. 2009 Oct;50(4):953-6. doi: 10.1016/j.jvs.2009.06.058.

DOI:10.1016/j.jvs.2009.06.058
PMID:19786244
Abstract

INTRODUCTION

Endovascular and surgical strategies have been used to manage patients with thrombosed vascular access for hemodialysis. We analyzed the evidence to see whether endovascular or surgical treatment has the best outcome in terms of primary success rate and long-term patency.

METHODS

We performed a systematic literature search of endovascular and surgical repair of thrombosed hemodialysis vascular access. The analysis included meta-analysis, randomized, and population-based studies of thrombosed arteriovenous fistulae and grafts.

RESULTS

One meta-analysis and eight randomized studies on the treatment of arteriovenous graft thrombosis were identified. Studies conducted before 2002 demonstrated a significantly better primary success rate and primary and secondary patencies of surgical thrombectomy vs endovascular intervention. After 2002, similar results of both techniques have been reported. Only population-based studies on the treatment of thrombosed autogenous arteriovenous fistulae have been published, showing similar outcome of surgical and endovascular intervention in terms of primary success. The long-term primary and secondary patencies are slightly better for surgical treatment, but this concerns only forearm fistulae.

CONCLUSIONS

The outcome of endovascular and surgical intervention for thrombosed vascular access is comparable, in particular for thrombosed prosthetic grafts. Surgical treatment of autogenous arteriovenous fistulae is likely to have benefit compared with endovascular means. Definitive randomized trials are needed to provide the level 1 evidence to resolve this latter issue.

摘要

引言

血管内治疗和外科手术策略已被用于处理患有血栓形成的血液透析血管通路的患者。我们分析了相关证据,以确定在初次成功率和长期通畅率方面,血管内治疗还是外科治疗具有最佳效果。

方法

我们对血栓形成的血液透析血管通路的血管内修复和外科修复进行了系统的文献检索。分析包括对血栓形成的动静脉内瘘和移植物的荟萃分析、随机对照研究和基于人群的研究。

结果

确定了一项关于动静脉移植物血栓形成治疗的荟萃分析和八项随机对照研究。2002年之前进行的研究表明,与血管内干预相比,外科血栓切除术的初次成功率以及初次和二次通畅率显著更高。2002年之后,两种技术报告了相似的结果。仅发表了基于人群的关于血栓形成的自体动静脉内瘘治疗的研究,显示手术和血管内干预在初次成功率方面有相似的结果。手术治疗的长期初次和二次通畅率略好,但这仅涉及前臂内瘘。

结论

血管内治疗和外科手术干预对血栓形成的血管通路的治疗效果相当,特别是对于血栓形成的人工血管移植物。与血管内治疗相比,自体动静脉内瘘的手术治疗可能更具优势。需要进行确定性的随机对照试验以提供一级证据来解决后一个问题。

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