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Radiotherapy: IMRT reduces xerostomia and potentially improves QoL.

作者信息

Eisbruch Avraham

出版信息

Nat Rev Clin Oncol. 2009 Oct;6(10):567-8. doi: 10.1038/nrclinonc.2009.143.

DOI:10.1038/nrclinonc.2009.143
PMID:19787001
Abstract
摘要

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Radiotherapy: IMRT reduces xerostomia and potentially improves QoL.放射治疗：调强适形放疗可减少口干症，并有可能改善生活质量。
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2
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Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):269-76. doi: 10.1016/j.ijrobp.2009.07.1734. Epub 2010 Jan 25.
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A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial results.一项针对接受调强放疗或三维放疗的头颈癌患者唾液功能保留情况的前瞻性研究：初步结果。
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本文引用的文献

1
Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a standardized follow-up program.调强放射治疗可降低放射诱导的发病率并改善健康相关生活质量：一项使用标准化随访方案的非随机前瞻性研究结果
Int J Radiat Oncol Biol Phys. 2009 May 1;74(1):1-8. doi: 10.1016/j.ijrobp.2008.07.059. Epub 2008 Dec 26.
2
Dose-effect relationships for the submandibular salivary glands and implications for their sparing by intensity modulated radiotherapy.下颌下唾液腺的剂量-效应关系及其在调强放射治疗中的保护意义。
Int J Radiat Oncol Biol Phys. 2008 Oct 1;72(2):373-82. doi: 10.1016/j.ijrobp.2007.12.033. Epub 2008 Mar 11.
3
长期口咽癌幸存者患者报告疲劳的相关风险因素。
Head Neck. 2022 Apr;44(4):952-963. doi: 10.1002/hed.26991. Epub 2022 Jan 27.
4
Determinants of patient-reported xerostomia among long-term oropharyngeal cancer survivors.长期口咽癌幸存者患者报告的口干症决定因素。
Cancer. 2021 Dec 1;127(23):4470-4480. doi: 10.1002/cncr.33849. Epub 2021 Aug 6.
5
Mouse parotid salivary gland organoids for the in vitro study of stem cell radiation response.用于体外研究干细胞辐射反应的鼠腮腺腺泡器官样体。
Oral Dis. 2021 Jan;27(1):52-63. doi: 10.1111/odi.13475. Epub 2020 Jun 29.
6
Dose-volume correlates of the prevalence of patient-reported trismus in long-term survivorship after oropharyngeal IMRT: A cross-sectional dosimetric analysis.口咽部调强放疗后长期生存患者报告的张口困难的发生率与剂量-体积学相关性：一项横断面剂量学分析。
Radiother Oncol. 2020 Aug;149:142-149. doi: 10.1016/j.radonc.2020.04.053. Epub 2020 May 6.
7
Predicting late radiation-induced xerostomia with parotid gland PET biomarkers and dose metrics.使用腮腺 PET 生物标志物和剂量指标预测晚期放射性口干。
Radiother Oncol. 2020 Jul;148:30-37. doi: 10.1016/j.radonc.2020.03.037. Epub 2020 Apr 6.
8
Unilateral cochlea sparing in locoregionally advanced head and neck cancer: a planning study.单侧耳蜗 sparing 在局部晚期头颈部癌症中的应用：一项计划研究。
Strahlenther Onkol. 2018 Dec;194(12):1124-1131. doi: 10.1007/s00066-018-1344-9. Epub 2018 Aug 14.
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Patient reported dry mouth: Instrument comparison and model performance for correlation with quality of life in head and neck cancer survivors.患者自述口干：用于相关性分析的仪器比较和模型表现，以及对头颈癌幸存者生活质量的影响。
Radiother Oncol. 2018 Jan;126(1):75-80. doi: 10.1016/j.radonc.2017.10.037. Epub 2017 Dec 8.
10
Outcomes of oral cavity cancer patients treated with surgery followed by postoperative intensity modulated radiation therapy.口腔癌患者接受手术联合术后调强放疗的治疗结果。
Oral Oncol. 2017 Sep;72:90-97. doi: 10.1016/j.oraloncology.2017.07.002. Epub 2017 Jul 16.
Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients.
早期鼻咽癌患者调强放射治疗对唾液腺功能影响的前瞻性随机研究
J Clin Oncol. 2007 Nov 1;25(31):4873-9. doi: 10.1200/JCO.2007.11.5501.
4
Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a randomized controlled clinical trial.调强放射治疗与传统放射治疗对早期鼻咽癌患者口干症及生活质量的影响：一项随机对照临床试验的初步报告
Int J Radiat Oncol Biol Phys. 2006 Nov 15;66(4):981-91. doi: 10.1016/j.ijrobp.2006.06.013.
5
Does radiation dose to the salivary glands and oral cavity predict patient-rated xerostomia and sticky saliva in head and neck cancer patients treated with curative radiotherapy?对头颈部癌患者进行根治性放射治疗时，唾液腺和口腔所接受的辐射剂量能否预测患者自评的口干和唾液黏稠情况？
Radiother Oncol. 2005 Nov;77(2):164-71. doi: 10.1016/j.radonc.2005.10.002. Epub 2005 Oct 26.
6
Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: which anatomic structures are affected and can they be spared by IMRT?头颈部癌放化疗后的吞咽困难与误吸：哪些解剖结构受到影响，调强放疗能否使其免受影响？
Int J Radiat Oncol Biol Phys. 2004 Dec 1;60(5):1425-39. doi: 10.1016/j.ijrobp.2004.05.050.
7
Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer.头颈部癌保留腮腺照射后的口干症及其预测因素
Int J Radiat Oncol Biol Phys. 2001 Jul 1;50(3):695-704. doi: 10.1016/s0360-3016(01)01512-7.
8
Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer.头颈部癌适形和调强放疗后腮腺的剂量、体积与功能关系
Int J Radiat Oncol Biol Phys. 1999 Oct 1;45(3):577-87. doi: 10.1016/s0360-3016(99)00247-3.