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利用离子迁移谱检测微生物挥发性有机化合物 (MVOCs)。

Detection of microbial volatile organic compounds (MVOCs) by ion-mobility spectrometry.

机构信息

BAM Federal Institute for Materials Research and Testing, 12200 Berlin, Germany.

出版信息

Anal Bioanal Chem. 2009 Dec;395(7):2313-23. doi: 10.1007/s00216-009-3147-4. Epub 2009 Sep 30.

Abstract

Traces of microbial volatile organic compounds (MVOCs) in air can indicate the presence of growth of moulds in the indoor environment. Ion-mobility spectrometry is a very promising method for detection of these MVOCs, because of its high sensitivity. For development of an in-situ method for detection of MVOCs, a portable ion-mobility spectrometer (IMS) was used and test gases of 14 MVOCs and their respective mixtures were investigated. IMS spectra were recorded as a function of concentration of MVOCs in air. Drift time and mobility of reactant ions formed in positive polarity mode were determined and correlated with the mass-to-charge ratio (m/z) of the MVOCs investigated. The estimated detection limit has a specific value for each MVOC and is in the range 3 to 96 microg m(-3) (1 to 52 ppb(V)). Indoor trials show that IMS can indicate hidden mould growth.

摘要

空气中微生物挥发性有机化合物 (MVOC) 的痕迹可以表明室内环境中霉菌的生长情况。离子迁移谱是一种非常有前途的检测这些 MVOC 的方法,因为它具有很高的灵敏度。为了开发用于检测 MVOC 的现场方法,使用了便携式离子迁移谱仪 (IMS),并对 14 种 MVOC 及其各自的混合物进行了测试。IMS 光谱作为空气中 MVOC 浓度的函数进行记录。确定了在正极性模式下形成的反应物离子的漂移时间和迁移率,并与所研究的 MVOC 的质荷比 (m/z) 相关联。每个 MVOC 的估计检测限都有一个特定的值,范围在 3 到 96μg m(-3)(1 到 52 ppb(V))。室内试验表明,IMS 可以指示隐藏的霉菌生长。

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