Benoit Jerome, Pruitt Amy F, Thrall Donald E
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA.
Vet Radiol Ultrasound. 2009 Sep-Oct;50(5):555-9. doi: 10.1111/j.1740-8261.2009.01573.x.
Despite the availability of commercial tissue equivalent bolus material, wet gauze has an application in radiation therapy to provide superior conformance to irregular contours. Wet gauze bolus has the potential to reduce air gaps between the bolus and surface, which could decrease surface dose if sufficiently large to disrupt electronic equilibrium. Wet gauze bolus is often fabricated and wetness judged qualitatively. We assessed the effect of specific gauze wetness levels, quantified in terms of physical density, at various field sizes with respect to their effectiveness as bolus material compared with Superflab. For large fields, > 7 x 7 cm2 in this study, wet gauze sponges with a physical density of 1.02 g/cm3 performed essentially identical to Superflab; at a smaller field size the wet gauze was slightly less effective, likely due to the heterogeneity of the gauze-water matrix. Gauze that was wetter, with a physical density of 1.2 g/cm3, or less wet, with a physical density of 0.75 g/cm3 was not as effective either due to enhanced photon absorption in the wetter sponges, or less effective establishment of electronic equilibrium in the less wet sponges. The presence of an air gap under Superflab led to reduced surface dose, especially for small fields and large air gaps. Thus, if Superflab use leads to poor contact with the skin, wet gauze having a physical density of 1.02 g/cm3 can be used as a substitute. Judging the water content of wet gauze subjectively is not acceptable as over- or under wetness can lead to decreased effectiveness of the bolus material.
尽管有商用组织等效填充材料,但湿纱布在放射治疗中仍有应用,因为它能更好地贴合不规则轮廓。湿纱布填充有可能减少填充材料与体表之间的气隙,如果气隙足够大以至于破坏电子平衡,那么就可以降低表面剂量。湿纱布填充通常是自制的,其湿度靠定性判断。我们评估了以物理密度量化的特定纱布湿度水平在不同射野尺寸下作为填充材料与超软等效物相比的效果。对于本研究中大于7×7平方厘米的大射野,物理密度为1.02克/立方厘米的湿纱布海绵与超软等效物的效果基本相同;在较小射野尺寸下,湿纱布的效果稍差,可能是由于纱布 - 水基质的不均匀性。湿度更高(物理密度为1.2克/立方厘米)或更低(物理密度为0.75克/立方厘米)的纱布效果都不佳,前者是因为更湿的海绵中光子吸收增强,后者是因为较干的海绵中电子平衡建立得较差。超软等效物下方存在气隙会导致表面剂量降低,尤其是对于小射野和大气隙情况。因此,如果使用超软等效物导致与皮肤接触不良,可以使用物理密度为1.02克/立方厘米的湿纱布作为替代品。主观判断湿纱布的含水量是不可取的,因为过湿或过干都会导致填充材料的有效性降低。