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镁合金作为植入物材料——Mg-RE 合金性能设计原理。

Magnesium alloys as implant materials--principles of property design for Mg-RE alloys.

机构信息

GKSS Research Centre, Institute of Materials Research, Max-Planck-Str 1, D-21502 Geesthacht, Germany.

出版信息

Acta Biomater. 2010 May;6(5):1714-25. doi: 10.1016/j.actbio.2009.09.010. Epub 2009 Sep 27.

DOI:10.1016/j.actbio.2009.09.010
PMID:19788945
Abstract

Magnesium alloys have attracted increasing interest in the past years due to their potential as implant materials. This interest is based on the fact that magnesium and its alloys are degradable during their time of service in the human body. Moreover magnesium alloys offer a property profile that is very close or even similar to that of human bone. The chemical composition triggers the resulting microstructure and features of degradation. In addition, the entire manufacturing route has an influence on the morphology of the microstructure after processing. Therefore the composition and the manufacturing route have to be chosen carefully with regard to the requirements of an application. This paper discusses the influence of composition and heat treatments on the microstructure, mechanical properties and corrosion behaviour of cast Mg-Gd alloys. Recommendations are given for the design of future degradable magnesium based implant materials.

摘要

在过去的几年中,由于镁合金作为植入材料的潜力,它们引起了越来越多的关注。这种兴趣基于这样一个事实,即镁及其合金在人体中的服役期间会降解。此外,镁合金提供了一种非常接近甚至类似于人体骨骼的性能。化学成分触发了降解的微观结构和特性。此外,整个制造路线对加工后的微观结构形态有影响。因此,在考虑应用要求的情况下,必须仔细选择成分和制造路线。本文讨论了成分和热处理对铸造 Mg-Gd 合金的微观结构、力学性能和腐蚀行为的影响。为未来可降解镁基植入材料的设计提出了建议。

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