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穿孔性阑尾炎:早期腹腔镜阑尾切除术是否合适?

Perforated appendicitis: is early laparoscopic appendectomy appropriate?

作者信息

Sleem Rami, Fisher Sabrina, Gestring Mark, Cheng Julius, Sangosanya Ayodele, Stassen Nicole, Bankey Paul

机构信息

Department of Surgery, University of Rochester Medical Center, Rochester, NY 14642, USA.

出版信息

Surgery. 2009 Oct;146(4):731-7; discussion 737-8. doi: 10.1016/j.surg.2009.06.053.

Abstract

BACKGROUND

Laparoscopic appendectomy for nonperforated appendicitis is associated with improved outcomes; however, laparoscopy has been challenged for perforated appendicitis owing to higher morbidity compared with open or staged procedures. The purpose of this study was to determine whether the laparoscopic approach for perforated appendicitis results in improved outcomes compared with open appendectomy.

METHODS

Postoperative patient records for confirmed perforated appendicitis from 2005 to 2008 were reviewed retrospectively. Demographics, surgical approach, conversion rate, and outcomes were tabulated, including length of stay (LOS), intra-abdominal and wound infections, and duration of antibiotic therapy.

RESULTS

The incidence of perforation was 27.9% in 885 total patients. The conversion rate from laparoscopic to open for perforated appendicitis was 16%. Hospital LOS was significantly lower in the laparoscopic group (P < .05). The incidence of postoperative abscess was not significantly different; however, the incidence of wound infection and duration of antibiotic therapy were significantly lower in the laparoscopic group (P < .05).

CONCLUSION

Successful laparoscopic appendectomy reduces LOS, antibiotic therapy, and wound infections compared with open appendectomy in perforated appendicitis without increasing the incidence of postoperative abscess. We conclude that perforated appendicitis can be managed effectively by laparoscopic appendectomy in a high percentage of patients with improved outcomes compared with open appendectomy.

摘要

背景

腹腔镜阑尾切除术治疗非穿孔性阑尾炎可带来更好的治疗效果;然而,与开放手术或分期手术相比,腹腔镜手术治疗穿孔性阑尾炎因发病率较高而受到质疑。本研究的目的是确定与开放阑尾切除术相比,腹腔镜手术治疗穿孔性阑尾炎是否能带来更好的治疗效果。

方法

回顾性分析2005年至2008年确诊为穿孔性阑尾炎患者的术后记录。将人口统计学资料、手术方式、中转率和治疗效果制成表格,包括住院时间(LOS)、腹腔内和伤口感染情况以及抗生素治疗持续时间。

结果

885例患者中穿孔发生率为27.9%。穿孔性阑尾炎的腹腔镜中转开放手术率为16%。腹腔镜组的住院时间显著缩短(P < 0.05)。术后脓肿发生率无显著差异;然而,腹腔镜组的伤口感染发生率和抗生素治疗持续时间显著降低(P < 0.05)。

结论

与开放阑尾切除术相比,成功的腹腔镜阑尾切除术可缩短穿孔性阑尾炎患者的住院时间、减少抗生素治疗及伤口感染,且不增加术后脓肿的发生率。我们得出结论,与开放阑尾切除术相比,腹腔镜阑尾切除术可有效治疗大部分穿孔性阑尾炎患者,并改善治疗效果。

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