兔眼中β-肾上腺素能受体的定量放射自显影
Quantitative autoradiography of beta-adrenergic receptors in rabbit eyes.
作者信息
Kahle G, Kaulen P, Wollensak J
机构信息
Universitäts-Augenklinik im Klinikum Charlottenburg, Freie Universität Berlin, F.R.G.
出版信息
Exp Eye Res. 1990 Nov;51(5):503-7. doi: 10.1016/0014-4835(90)90080-e.
Beta-adrenergic receptors were localized and quantified with autoradiographic methods in frozen sections of eyes of albino rabbits using [125I]cyanopindolol and [3H]dihydroalprenolol. Quantification in albino rabbits revealed highest beta 2-adrenoceptor densities in the ciliary body, the corneal epithelium and the corneal endothelium. Moreover, the iris showed significant amounts of specific binding, whereas the retina and sclera are nearly free of these receptors.
采用放射自显影法，使用[125I]氰基吲哚洛尔和[3H]二氢阿普洛尔，对白化兔眼的冰冻切片中的β-肾上腺素能受体进行定位和定量。对白化兔的定量分析显示，睫状体、角膜上皮和角膜内皮中的β2-肾上腺素能受体密度最高。此外，虹膜显示出大量特异性结合，而视网膜和巩膜几乎没有这些受体。
Zotero 插件