School of Public Health, Peking University, Beijing, China.
Trop Med Int Health. 2009 Dec;14(12):1475-83. doi: 10.1111/j.1365-3156.2009.02403.x. Epub 2009 Sep 27.
Despite sustained efforts for its control made over the past 50+ years, the re-emergence of schistosomiasis in China was noted around the turn of the new millennium. Consequently, a new integrated strategy was proposed to stop the contamination of schistosome eggs to the environment, which emphasizes health education, access to clean water and adequate sanitation, mechanization of agriculture and fencing of water buffaloes, along with chemotherapy. Validation of this integrated control strategy in four pilot counties in the provinces of Anhui, Hubei, Hunan and Jiangxi revealed significant reductions in the rate of Schistosoma japonicum infection in humans and intermediate host snails. Importantly, this strategy showed an impact on diseases beyond schistosomiasis, signified by concomitant reductions in the prevalence of soil-transmitted helminth infections. In view of China's new integrated strategy for transmission control of schistosomiasis showing an ancillary benefit on other helminthic diseases, we encourage others to investigate the scope and limits of integrated control of neglected tropical diseases.
尽管过去 50 多年来一直在努力控制血吸虫病，但在新千年之交，中国的血吸虫病再次出现。因此，提出了一种新的综合策略来阻止血吸虫卵对环境的污染，该策略强调健康教育、获得清洁水和充足的卫生设施、农业机械化和水牛围栏以及化疗。在安徽、湖北、湖南和江西四个试点县验证了这种综合控制策略，结果显示人类和中间宿主钉螺的日本血吸虫感染率显著降低。重要的是，这种策略对血吸虫病以外的疾病也产生了影响，这表现为土壤传播性蠕虫感染的患病率同时降低。鉴于中国新的血吸虫病传播控制综合策略对其他寄生虫病也有辅助作用，我们鼓励其他人研究综合控制被忽视的热带病的范围和限制。
