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腰椎管狭窄症患者步态变异性测量:第 A 部分。与健康受试者的比较。

Gait variability measurements in lumbar spinal stenosis patients: part A. Comparison with healthy subjects.

机构信息

TEI of Crete, Biomechanics Laboratory, Estavromenos, PO Box 1939, Crete, Greece.

出版信息

Physiol Meas. 2009 Nov;30(11):1171-86. doi: 10.1088/0967-3334/30/11/003. Epub 2009 Oct 1.

Abstract

The objective of this study is to compare the gait variability of patients with lumbar spinal stenosis (experimental group) with healthy individuals (control group). The hypothesis is that the preoperative gait variability of the experimental group is higher than the control group. The experimental group consisted of 35 adults (18 males, 17 females). The subjects of the experimental group suffered exclusively from spinal stenosis. The patients were determined by MRI scans. A tri-axial accelerometer sensor was used for the gait measurement, and differential entropy algorithm was used to quantify the gait acceleration signal. The Oswestry Low Back Pain Questionnaire was used to determine the condition on the day of the measurement. Receiver operating characteristic (ROC) was utilized to assess the diagnostic value of the method and determine a cut-off value. There is a statistically significant difference between gait variability in the control group and the experimental group. ROC analysis determines a cut-off differential entropy value. The cut-off value has a 97.6% probability of separating patients with spinal stenosis from healthy subjects. The Oswestry Low Back Questionnaire is well correlated with the spectral differential entropy values.

摘要

本研究旨在比较腰椎管狭窄症患者(实验组)与健康个体(对照组)的步态变异性。假设实验组术前步态变异性高于对照组。实验组由 35 名成年人(18 名男性,17 名女性)组成。实验组的受试者仅患有椎管狭窄症。患者通过 MRI 扫描确定。三轴加速度传感器用于步态测量,差分熵算法用于量化步态加速信号。Oswestry 下腰痛问卷用于测量当天确定病情。接收者操作特征 (ROC) 用于评估该方法的诊断价值并确定截止值。对照组和实验组之间的步态变异性存在统计学显著差异。ROC 分析确定了差分熵的截止值。截止值有 97.6%的概率可以将患有脊柱狭窄症的患者与健康受试者区分开来。Oswestry 下腰痛问卷与频谱差分熵值具有良好的相关性。

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