Peñalva M A, Moya A, Dopazo J, Ramón D
Centro de Investigaciones Biológicas del C.S.I.C., Madrid, Spain.
Proc Biol Sci. 1990 Sep 22;241(1302):164-9. doi: 10.1098/rspb.1990.0081.
Evolutionary distances between bacterial and fungal isopenicillin N synthetase (IPNS) genes have been compared to distances between the corresponding 5S rRNA genes. The presence of sequences homologous to the IPNS gene has been examined in DNAs from representative prokaryotic organisms and Ascomycotina. The results of both analyses strongly support two different events of horizontal transfer of the IPNS gene from bacteria to filamentous fungi. This is the first example of such a type of transfer from prokaryotes to eukaryotes.
已将细菌和真菌的异青霉素N合成酶（IPNS）基因之间的进化距离与相应的5S rRNA基因之间的距离进行了比较。在来自代表性原核生物和子囊菌纲的DNA中检测了与IPNS基因同源的序列。两项分析的结果都有力地支持了IPNS基因从细菌水平转移到丝状真菌的两种不同事件。这是此类从原核生物转移到真核生物的第一个例子。
