Saĭfulina N A, Arkhipov G S, Stepanov A F, Gusev Iu A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1990;90(7):87-90.
As many as 43 patients with first diagnosed paranoid schizophrenia running a shift-like course were examined for the blood counts of T and B lymphocytes with regard to the treatment conducted and disease standing. The patients received 3 types of the treatment: insulin, neuroleptics and combined treatment (insulin plus neuroleptics). During the treatment and after it, the content of B lymphocytes remained practically unchanged (p greater than 0.05) in all the patients. The content of T lymphocytes was reduced throughout the whole period of affliction with schizophrenia. However, during the combined treatment of the disease, a tendency towards increase of T cells was revealed, which coincided with the best clinical indicators.
对43例首次诊断为偏执型精神分裂症且病情呈间歇性病程的患者，就其接受的治疗及疾病状况进行了T淋巴细胞和B淋巴细胞的血细胞计数检查。患者接受了3种治疗：胰岛素治疗、抗精神病药物治疗以及联合治疗（胰岛素加抗精神病药物）。在治疗期间及治疗后，所有患者的B淋巴细胞含量实际上保持不变（p＞0.05）。在整个精神分裂症患病期间，T淋巴细胞含量均降低。然而，在该疾病的联合治疗期间，发现T细胞有增加的趋势，这与最佳临床指标相符。
