Libin Cardiovascular Institute of Alberta, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1.
Europace. 2009 Oct;11(10):1369-74. doi: 10.1093/europace/eup106.
To develop a brief syncope-specific measure of health-related quality of life.
One hundred and fourteen patients with syncope completed a 48-item questionnaire derived from a generic measure of quality of life (the EQ-5D), the Syncope Functional Status Questionnaire, a depression scale (the CES-D) and historical symptoms. From these, clinical impact methodology was used to derive 12-item Impact of Syncope on Quality of Life (ISQL). The ISQL correlated with the number of syncopal spells in the previous year (r = 0.35), self-perceived health status (r = -0.55), the three scores from the SFSQ: [impairment (r = 0.77), fear and worry (r = 0.72), syncope dysfunction (r = 0.82), and depression (r = 0.62)], illustrating its convergent validity with these concepts. Known group differences were evident between patients who exhibited reduced quality of life on the EQ-5D and those who did not. There was no significant correlation between ISQL score and age or gender. ISQL score correlated better with the frequency of spells in the previous year than years prior to the previous year.
The ISQL is a brief valid measure of the impact of syncope on quality of life. It measures impairment, fear, depression, and physical limitations, and correlates with recent syncope frequency.
开发一种针对晕厥的简短健康相关生活质量测量工具。
114 名晕厥患者完成了一份 48 项问卷，该问卷源自生活质量通用量表（EQ-5D）、晕厥功能状态问卷、抑郁量表（CES-D）和既往症状。采用临床影响方法从这些问卷中得出 12 项晕厥对生活质量的影响（ISQL）。ISQL 与前一年晕厥发作次数相关（r = 0.35），与自我感知健康状况相关（r = -0.55），与 SFSQ 的三个评分相关：[功能障碍（r = 0.77）]、恐惧和担忧（r = 0.72）、晕厥功能障碍（r = 0.82）和抑郁（r = 0.62）]，表明其与这些概念具有收敛效度。在 EQ-5D 上表现出生活质量降低的患者与没有降低的患者之间存在明显的已知组间差异。ISQL 评分与年龄或性别无显著相关性。ISQL 评分与前一年的发作频率比前一年之前的年份更相关。
ISQL 是一种针对晕厥对生活质量影响的简短有效测量工具。它可测量功能障碍、恐惧、抑郁和身体限制，并与近期晕厥发作频率相关。
