ProSeq3 软件处理和多基因数据集的群体遗传分析。
Processing and population genetic analysis of multigenic datasets with ProSeq3 software.
机构信息
Department of Plant Sciences, University of Oxford, South Parks Rd, Oxford OX1 3RB, UK.
出版信息
Bioinformatics. 2009 Dec 1;25(23):3189-90. doi: 10.1093/bioinformatics/btp572. Epub 2009 Oct 1.
Abstract
MOTIVATION
The current tendency in molecular population genetics is to use increasing numbers of genes in the analysis. Here I describe a program for handling and population genetic analysis of DNA polymorphism data collected from multiple genes. The program includes a sequence/alignment editor and an internal relational database that simplify the preparation and manipulation of multigenic DNA polymorphism datasets. The most commonly used DNA polymorphism analyses are implemented in ProSeq3, facilitating population genetic analysis of large multigenic datasets. Extensive input/output options make ProSeq3 a convenient hub for sequence data processing and analysis.
AVAILABILITY
The program is available free of charge from http://dps.plants.ox.ac.uk/sequencing/proseq.htm.
摘要
动机
分子群体遗传学的当前趋势是在分析中使用越来越多的基因。在这里，我描述了一个用于处理和分析从多个基因中收集的 DNA 多态性数据的程序。该程序包括一个序列/对齐编辑器和一个内部关系数据库，可简化多基因 DNA 多态数据集的准备和操作。ProSeq3 中实现了最常用的 DNA 多态性分析，可方便地对大型多基因数据集进行群体遗传分析。广泛的输入/输出选项使 ProSeq3 成为方便的序列数据处理和分析中心。
可用性
该程序可从 http://dps.plants.ox.ac.uk/sequencing/proseq.htm 免费获得。
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