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因触须诺卡菌导致的菌血症和肾上腺脓肿:一例病例报告并文献复习。

Bacteremia and adrenal gland abscess due to Nocardia cyriacigeorgica: a case report and review.

机构信息

Infectious Disease Department, University Hospital of Saint Etienne, 42055, Saint-Étienne, France.

Department of Radiology, University Hospital of Saint Etienne, 42055, Saint-Étienne, France.

出版信息

BMC Infect Dis. 2022 Dec 29;22(1):966. doi: 10.1186/s12879-022-07839-9.

Abstract

BACKGROUND

Nocardia cyriacigeorgica is one of the most common Nocardia species found in human infections, recently reclassified. Even though Nocardia may affect all organs by hematogenous dissemination, bacteremia are uncommon. Among all possible dissemination sites, the involvement of the adrenal glands is particularly rare.

CASE PRESENTATION

We report here a rare case of Nocardia disseminated infection with notably bacteremia and adrenal gland abscess, in a 77-years-old immunocompetent man. Adrenal gland abscess diagnosis was made by imaging (computerized tomography, magnetic resonance and positron emission tomography scan). A complete regression of all lesions including the left adrenal gland was obtained after 6 months of antibiotics. A review of literature was also performed.

CONCLUSION

Nocardia bacteremia is a rare event but blood cultures may help to improve detection of Nocardia spp. in a non-invasive way. Adrenal abscess due to Nocardia spp. is very rare with only fourteen cases reported in the literature, but it is a true cause of adrenal masses. Our report suggests that clinician should be aware of this rare location and prioritize a non-invasive diagnosis strategy.

摘要

背景

触须状诺卡菌是人类感染中最常见的诺卡菌属之一,最近已重新分类。尽管诺卡菌可能通过血源性播散影响所有器官,但菌血症并不常见。在所有可能的播散部位中,肾上腺受累尤为罕见。

病例介绍

我们在此报告一例罕见的触须状诺卡菌播散感染病例,该患者为 77 岁免疫功能正常的男性,伴有明显菌血症和肾上腺脓肿。通过影像学(计算机断层扫描、磁共振和正电子发射断层扫描)诊断为肾上腺脓肿。在使用抗生素 6 个月后,所有病变(包括左侧肾上腺)完全消退。我们还进行了文献复习。

结论

诺卡菌菌血症较为罕见,但血培养可能有助于以非侵入性方式提高对诺卡菌属的检出率。由诺卡菌属引起的肾上腺脓肿非常罕见,文献中仅报道了 14 例,但它是肾上腺肿块的一个真正病因。我们的报告提示临床医生应注意这一罕见部位,并优先采取非侵入性诊断策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a50/9801643/9f89a703031c/12879_2022_7839_Fig1_HTML.jpg

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