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[从植物来源中寻找新型生物活性天然产物——新结构与生物活性——]

[Search of novel bioactive natural products from plant sources--novel structures and biological activities--].

作者信息

Furukawa Hiroshi

机构信息

Faculty of Pharmacy, Meijo University, Nagoya, Japan.

出版信息

Yakugaku Zasshi. 2009 Oct;129(10):1155-75. doi: 10.1248/yakushi.129.1155.

Abstract

Over 30 years, our laboratory has been involved in the search of bioactive natural products from plant sources of several plant families, Rutaceae, Guttiferae, Avicenniaceae, and so on. In this review, novel structures of acridone alkaloids, carbazole alkaloids, coumarins, depsidones, and so on isolated in our laboratory will be showed. In addition, some results of assay of biological activities of the isolated compounds also will be described.

摘要

30多年来,我们的实验室一直致力于从芸香科、藤黄科、白骨壤科等多个植物科的植物来源中寻找生物活性天然产物。在这篇综述中,将展示我们实验室分离得到的吖啶酮生物碱、咔唑生物碱、香豆素、缩酚酸酮等的新结构。此外,还将描述所分离化合物的一些生物活性测定结果。

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