Center for Natural Medicine and Prevention, Maharishi University of Management Research Institute, Maharishi Vedic City, Iowa, USA.
Am J Hypertens. 2009 Dec;22(12):1326-31. doi: 10.1038/ajh.2009.184. Epub 2009 Oct 1.
Psychological distress contributes to the development of hypertension in young adults. This trial assessed the effects of a mind-body intervention on blood pressure (BP), psychological distress, and coping in college students.
This was a randomized controlled trial (RCT) of 298 university students randomly allocated to either the Transcendental Meditation (TM) program or wait-list control. At baseline and after 3 months, BP, psychological distress, and coping ability were assessed. A subgroup of 159 subjects at risk for hypertension was analyzed similarly.
Changes in systolic BP (SBP)/diastolic BP (DBP) for the overall sample were -2.0/-1.2 mm Hg for the TM group compared to +0.4/+0.5 mm Hg for controls (P = 0.15, P = 0.15, respectively). Changes in SBP/DBP for the hypertension risk subgroup were -5.0/-2.8 mm Hg for the TM group compared to +1.3/+1.2 mm Hg for controls (P = 0.014, P = 0.028, respectively). Significant improvements were found in total psychological distress, anxiety, depression, anger/hostility, and coping (P values < 0.05). Changes in psychological distress and coping correlated with changes in SBP (P values < 0.05) and DBP (P values < 0.08).
This is the first RCT to demonstrate that a selected mind-body intervention, the TM program, decreased BP in association with decreased psychological distress, and increased coping in young adults at risk for hypertension. This mind-body program may reduce the risk for future development of hypertension in young adults.
心理困扰会导致年轻人高血压的发生。本试验评估了身心干预对大学生血压(BP)、心理困扰和应对能力的影响。
这是一项针对 298 名大学生的随机对照试验(RCT),随机分为 transcendental meditation(TM)组或候补名单对照组。在基线和 3 个月后,评估 BP、心理困扰和应对能力。对 159 名有高血压风险的受试者进行了类似的亚组分析。
总体样本的收缩压(SBP)/舒张压(DBP)变化,TM 组为-2.0/-1.2mmHg,对照组为+0.4/+0.5mmHg(P=0.15,P=0.15)。高血压风险亚组的 SBP/DBP 变化,TM 组为-5.0/-2.8mmHg,对照组为+1.3/+1.2mmHg(P=0.014,P=0.028)。TM 组的总心理困扰、焦虑、抑郁、愤怒/敌意和应对能力均显著改善(P 值均<0.05)。心理困扰和应对能力的变化与 SBP(P 值<0.05)和 DBP(P 值<0.08)的变化相关。
这是第一项 RCT 研究表明,一种选择的身心干预措施——TM 方案,可降低血压,同时降低高血压风险的年轻人的心理困扰,提高应对能力。这种身心方案可能会降低年轻人未来发生高血压的风险。