Dolmatov I Iu
Zh Obshch Biol. 2009 Jul-Aug;70(4):316-27.
Five variants of regeneration of the digestive system in holothurians are recognized on the basis of original and published data. They depend on presence of organs remains, ability of cells for de-differentiation, damage type, and ontogenetic stage. Regeneration occurs in all cases by means of differentiated cells, no stem cells participation was recorded in any species studied. It is suggested that the entire diversity of recovering reactions observed for the holothurians gut is not an evolutionary innovation in Holothuroidea but evolved on the basis of already existing mechanisms of regeneration and blastogenesis in the ancient echinodermats. Analysis of khown data indicates that holothurians possess two groups of recovering processes, one of which is close to embryonic development and another to blastogenesis by respective mechanisms. This may indicate probable polyphyletic origin of reparative regeneration in Echinodermata.
根据原始数据和已发表的数据，确认了海参消化系统再生的五种变体。它们取决于器官残余物的存在、细胞去分化的能力、损伤类型和个体发育阶段。在所有情况下，再生都是通过分化细胞进行的，在所研究的任何物种中都未记录到干细胞的参与。有人认为，海参肠道观察到的恢复反应的全部多样性并非海参纲的进化创新，而是在古代棘皮动物已有的再生和芽生机制基础上进化而来的。对已知数据的分析表明，海参具有两组恢复过程，其中一组通过各自的机制与胚胎发育相近，另一组与芽生相近。这可能表明棘皮动物修复性再生可能具有多系起源。
