Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.
Cancer Res Treat. 2009 Sep;41(3):182-5. doi: 10.4143/crt.2009.41.3.182. Epub 2009 Sep 28.
Plasmablastic lymphoma (PBL) of the oral cavity is an acquired immunodeficiency syndrome-related lymphoma. The immunophenotype of this disease is associated with poor expression of B-cell markers but a positive reactivity for plasma cell markers. PBL is highly aggressive and responds poorly to treatment. Although originally described in the oral cavity, this disease can occur in other body niches. Here, we describe a very rare case of PBL in the anal canal of a 40-year-old woman with human immunodeficiency virus infection. The malignant cells were positive for Epstein-Barr virus and human herpes virus 8.
口腔黏膜性浆细胞瘤（PBL）是一种获得性免疫缺陷综合征相关的淋巴瘤。这种疾病的免疫表型与 B 细胞标志物表达不良有关，但浆细胞标志物呈阳性反应。PBL 侵袭性强，对治疗反应不佳。虽然最初在口腔中描述，但这种疾病也可能发生在其他身体部位。在这里，我们描述了一例非常罕见的人类免疫缺陷病毒感染 40 岁女性肛管 PBL 病例。恶性细胞对 EBV 和 HHV-8 呈阳性。
