雌激素在心血管系统中的作用。

Estrogen actions in the cardiovascular system.

机构信息

Molecular Cardiology Research Institute, Tufts Medical Center, Tufts University School of Medicine, Boston, USA.

出版信息

Climacteric. 2009;12 Suppl 1:18-21. doi: 10.1080/13697130903020291.

DOI:10.1080/13697130903020291

PMID:19811235

Abstract

This brief review summarizes the current state of the field for estrogen receptor actions in the cardiovascular system and the cardiovascular effects of hormone replacement therapy (HRT). It is organized into three parts: a short Introduction and overview of the current view of how estrogen works on blood vessels; a summary of the current status of clinical information regarding HRT and cardiovascular effects; and an update on state-of-the-art mouse models of estrogen action using estrogen receptor knockout mice.

摘要

这篇简要综述总结了雌激素在心血管系统中的作用以及激素替代疗法（HRT）的心血管效应的研究现状。全文分为三部分：简短的引言和对目前雌激素作用于血管机制的概述；关于 HRT 和心血管效应的临床信息的现状总结；以及利用雌激素受体敲除小鼠的最新雌激素作用的小鼠模型。