Chemistry and Environment College, Southern China Normal University, Guangzhou, People's Republic of China.
Integr Cancer Ther. 2009 Sep;8(3):283-7. doi: 10.1177/1534735409343693.
Photodynamic therapy (PDT) is an established therapeutic method, first approved by the FDA for certain kinds of cancer in 1998. There are also increasing data to show that a related procedure, sonodynamic therapy (SDT), is a promising new modality for cancer treatment. Here, the authors report clinical results in 3 advanced refractory breast cancer patients who were treated using a combination of sonodynamic and photodynamic therapy (SPDT), along with conventional therapies. All 3 patients had pathologically proven metastatic breast carcinoma. These widely disseminated carcinomas had ultimately failed to respond to conventional therapy. A new sensitizing agent, Sonoflora 1 (SF1) was administered sublingually; then, after a 24-hour delay, patients were treated with a combination of light and ultrasound. All patients had significant partial or complete responses. SPDT is a promising new therapeutic combination for the treatment of breast cancer.
光动力疗法（PDT）是一种已确立的治疗方法，于 1998 年首次获得 FDA 批准用于治疗某些癌症。也有越来越多的数据表明，一种相关的程序，声动力学疗法（SDT），是一种有前途的癌症治疗新方法。在这里，作者报告了 3 例晚期难治性乳腺癌患者的临床结果，这些患者采用声动力和光动力治疗（SPDT）联合常规治疗。所有 3 例患者均经病理证实患有转移性乳腺癌。这些广泛传播的癌症最终对常规治疗没有反应。一种新的敏化剂 Sonoflora 1（SF1）被舌下给药；然后，在 24 小时延迟后，患者接受光和超声联合治疗。所有患者均有明显的部分或完全缓解。SPDT 是治疗乳腺癌的一种很有前途的新治疗联合用药。
