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[用单克隆抗体-玫瑰花环试剂法测定肺结核患者的淋巴细胞亚群]

[Determination of lymphocyte subsets in pulmonary tuberculosis by Mc-Ab- rosette reagent method].

作者信息

Fan X H, Gao H

机构信息

Wuhan Tuberculosis Hospital.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1990 Oct;13(5):297-8, 319.

PMID:1982248
Abstract

The lymphocyte subsets in peripheral blood were determined in 73 cases of active pulmonary tuberculosis and 40 healthy subjects using rosette reagent of monoclonal antibody (McAb) to anti-T lymphocyte. The results showed that the percentages of T3, T4, T8, and T4/T8 ratio were 54.3 +/- 6.7%, 34.3 +/- 7.9%, 35.5 +/- 10.0%, 1.0 +/- 0.4 of patients group 66.3 +/- 7.9%, 45.3 +/- 6.3%, 29.9 +/- 5.8% and 1.6 +/- 0.3 of healthy control group respectively. There was statistically significant difference between these two groups (P less than 0.01).

摘要

采用抗T淋巴细胞单克隆抗体(McAb)花环试剂,对73例活动性肺结核患者和40名健康对照者外周血淋巴细胞亚群进行了检测。结果显示,患者组T3、T4、T8百分比及T4/T8比值分别为54.3±6.7%、34.3±7.9%、35.5±10.0%、1.0±0.4;健康对照组分别为66.3±7.9%、45.3±6.3%、29.9±5.8%、1.6±0.3。两组间差异有统计学意义(P<0.01)。

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