Fenn Larissa S, McLean John A
Department of Chemistry, Vanderbilt Institute of Chemical Biology, Vanderbilt Institute of Integrative Biosystems Research and Education, Vanderbilt University, 7330 Stevenson Center, Nashville, TN 37235, USA.
Mol Biosyst. 2009 Nov;5(11):1298-302. doi: 10.1039/b909745g. Epub 2009 Aug 10.
Simultaneous glycoproteomic characterization using rapid (mus to ms) structural separations provided by ion mobility-mass spectrometry (IM-MS) is described. Advantages from using both ESI and MALDI ion sources are presented with future implications toward high throughput glycan and glycoconjugate characterization.
本文描述了利用离子淌度质谱（IM-MS）提供的快速（从分子到质谱）结构分离技术进行同步糖蛋白质组学表征。文中展示了使用电喷雾电离（ESI）和基质辅助激光解吸电离（MALDI）离子源的优势，以及对高通量聚糖和糖缀合物表征的未来意义。
