One billion years of p53/p63/p73 evolution.
作者信息
Belyi Vladimir A, Levine Arnold J
机构信息
Institute for Advanced Study, Princeton, NJ 08540, USA.
出版信息
Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17609-10. doi: 10.1073/pnas.0910634106. Epub 2009 Oct 13.
Abstract
摘要
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本文引用的文献
1
The origins and evolution of the p53 family of genes.p53 基因家族的起源与进化。
Cold Spring Harb Perspect Biol. 2010 Jun;2(6):a001198. doi: 10.1101/cshperspect.a001198. Epub 2009 Dec 16.
2
Structural evolution of p53, p63, and p73: implication for heterotetramer formation.p53、p63和p73的结构演变：对异源四聚体形成的影响。
Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17705-10. doi: 10.1073/pnas.0905867106. Epub 2009 Oct 7.
3
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway.p53-p21 通路对诱导多能干细胞生成的抑制作用。
Nature. 2009 Aug 27;460(7259):1132-5. doi: 10.1038/nature08235. Epub 2009 Aug 9.
4
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells.永生化消除了细胞重编程为诱导多能干细胞过程中的一个障碍。
Nature. 2009 Aug 27;460(7259):1145-8. doi: 10.1038/nature08285. Epub 2009 Aug 9.
5
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity.p53介导的DNA损伤反应限制重编程以确保诱导多能干细胞基因组的完整性。
Nature. 2009 Aug 27;460(7259):1149-53. doi: 10.1038/nature08287. Epub 2009 Aug 9.
6
The Ink4/Arf locus is a barrier for iPS cell reprogramming.Ink4/Arf基因座是诱导多能干细胞重编程的一个障碍。
Nature. 2009 Aug 27;460(7259):1136-9. doi: 10.1038/nature08290. Epub 2009 Aug 9.
7
Linking the p53 tumour suppressor pathway to somatic cell reprogramming.将p53肿瘤抑制通路与体细胞重编程联系起来。
Nature. 2009 Aug 27;460(7259):1140-4. doi: 10.1038/nature08311. Epub 2009 Aug 9.
8
Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans.p53 通路中的单核苷酸多态性调节人类生育能力。
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TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.TAp73基因敲除显示出基因组不稳定，并伴有不育和肿瘤抑制功能。
Genes Dev. 2008 Oct 1;22(19):2677-91. doi: 10.1101/gad.1695308. Epub 2008 Sep 19.
10
p53 regulates maternal reproduction through LIF.p53通过白血病抑制因子调控母体生殖。
Nature. 2007 Nov 29;450(7170):721-4. doi: 10.1038/nature05993.
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