Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN, USA.
Int J Environ Res Public Health. 2009 Sep;6(9):2426-35. doi: 10.3390/ijerph6092426. Epub 2009 Sep 10.
This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3-6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.
这项回顾性基于人群的研究评估了饮酒对急性呼吸窘迫综合征（ARDS）发展的影响。入院时根据患者和/或家属提供的信息来量化饮酒量。ARDS 根据美国-欧洲共识会议（AECC）定义。在 1422 名危重症奥姆斯特德县居民中，有 1357 人的病历中有关于饮酒的信息，其中 77 人（6%）发生了 ARDS。有 97 名（7%）患者报告有大量饮酒史（每天超过两杯）。在校正了潜在的 ARDS 危险因素（误吸、化疗、高危手术、胰腺炎、脓毒症、休克）、吸烟、肝硬化和性别后，大量饮酒史与 ARDS 发展的风险增加相关（比值比 2.9，95%CI 1.3-6.2）。这项基于人群的研究证实，过量饮酒与 ARDS 风险增加相关。
