Tavallaee Mahkam, Rad Mahnaz Mahmoudi
J Med Case Rep. 2009 Jul 6;3:7368. doi: 10.4076/1752-1947-3-7368.
Fluconazole is a widely used antifungal agent with a possible side effect of fixed drug eruption. However, this adverse drug effect is absent from the reported list of possible side effects of fluconazole. We are presenting a rare case in our report.
A 25-year-old Iranian woman developed fixed drug eruptions on different sites of her body after taking five doses of fluconazole to treat vaginal candidiasis. A positive patch test, positive oral challenge test and skin biopsy were all found to be consistent with fixed drug eruption.
Fluconazole is a widely prescribed drug, used mainly to treat candidiasis. Fixed drug eruption as a possible side effect of Fluconazole is not well known and thus, the lesions may be misdiagnosed and mistreated. Based on our findings, which are consistent with a number of other practitioners, we recommend adding fixed drug eruption to the list of possible side effects of fluconazole.
氟康唑是一种广泛使用的抗真菌药物，可能会产生固定性药疹这一副作用。然而，在已报道的氟康唑可能的副作用列表中并未提及这种药物不良反应。我们在本报告中呈现了一个罕见病例。
一名25岁的伊朗女性在服用五剂氟康唑治疗阴道念珠菌病后，身体不同部位出现了固定性药疹。斑贴试验阳性、口服激发试验阳性以及皮肤活检结果均与固定性药疹相符。
氟康唑是一种广泛处方用药，主要用于治疗念珠菌病。固定性药疹作为氟康唑可能的副作用并不广为人知，因此，这些皮损可能会被误诊和误治。基于我们与其他一些从业者一致的研究结果，我们建议将固定性药疹添加到氟康唑可能的副作用列表中。
