Morata G, Macías A, Urquía N, González-Reyes A
Centro de Biologia Molecular, Universidad Autónoma de Madrid, Spain.
Semin Cell Biol. 1990 Jun;1(3):219-27.
Region specific differentiation in Drosophila, (and possibly in many other higher organisms), is controlled by the activity of families of transcription factors encoded by the homoeotic genes. In Drosophila these genes are clustered in two complexes: the Antennapedia complex is responsible for directing the differentiation of the head and thoracic body segments whereas the bithorax complex controls the differentiation of the thorax and abdomen. The precise way in which these genes work is still a mystery but both the levels and combinations of gene activities play an important role in directing the development of individual segments.
果蝇（可能还有许多其他高等生物）中的区域特异性分化是由同源异型基因编码的转录因子家族的活性所控制的。在果蝇中，这些基因聚集在两个复合体中：触角足复合体负责指导头部和胸部体节的分化，而双胸复合体则控制胸部和腹部的分化。这些基因发挥作用的确切方式仍是个谜，但基因活性的水平和组合在指导各个体节的发育中都起着重要作用。
