Ingham P W
J Embryol Exp Morphol. 1985 Oct;89:349-65.
The requirement for the trithorax gene during imaginal cell proliferation has been analysed by clonal analysis. Clones carrying the allelic Regulator of bithorax and induced by mitotic recombination at different developmental stages. The results indicate that the trithorax gene is required at least until the beginning of the third larval instar to ensure the correct differentiation of head, thoracic, and abdominal structures, and are consistent with a role for the gene in maintaining the appropriate levels of Antennapedia and bithorax complex expression.
通过克隆分析，对成虫盘细胞增殖过程中三体胸基因的需求进行了分析。携带双胸等位调节基因的克隆，通过在不同发育阶段进行有丝分裂重组诱导产生。结果表明，三体胸基因至少在第三龄幼虫初期仍有需求，以确保头部、胸部和腹部结构的正确分化，这与该基因在维持触角足和双胸复合体适当表达水平方面的作用一致。
