Marickar Y M Fazil, Nair Nandu, Varma Gayathri, Salim Abiya
Department of Surgery, Zensa Hospital, Trivandrum, 695009, India.
Urol Res. 2009 Dec;37(6):369-76. doi: 10.1007/s00240-009-0224-2. Epub 2009 Oct 16.
This paper attempts to assess the current status of the various modalities of available treatment for urinary stone disease in the Kerala scenario. A total of 300 patients who attended the stone clinic with urinary stone disease and had stones retrieved by different means were selected for the study. Their clinical symptoms, demographic profile, size, number and position of stones, metabolic profiles, retrieval modalities and end result of treatment in terms of stone clearance were assessed. Instances of failure, incomplete clearance and complication events were noted. Based on the experiences, a flowchart was created for appropriate decision-making in urinary stone management. The modalities of retrieval included nephrectomy, nephrolithotomy, pyelo-nephrolithotomy, extended pyelolithotomy, pyelolithotomy, ureterolithotomy, cystolithotomy, urethrolithotomy, ESWL, PCNL, URS, cystolithotripsy, urethrolithotripsy and spontaneous passage. The clearance rate of stone was maximum in open surgery. The extent of stone clearance by ESWL depended on various factors. PCNL was mostly limited by the difficulties in achieving puncture at the stone site. Availability of a variety of flexible nephroscopes also altered the success rate of the procedure. There were good success rates in pushing stones from the ureter to the pelvis followed by PCNL. In patients who had successful PCNL, postoperative morbidity was significantly reduced in terms of the number of days of hospitalization, time taken for return to work, absence of urinary leak, site infection, urinoma formation and urinary tract infection. URS was performed in many patients and stones retrieved. However, the indication for the procedure remains doubtful as the size of most of the stones thus retrieved was less than 6 mm. These would have passed out spontaneously or with chemotherapeutic support. URS, lithotripsy and basketting were confronted by upward migration of stones to the kidney, requiring further procedures for retrieval. Introduction of double J stents helped in relieving urinary obstruction, particularly in patients presenting with anuria, but retained stents, forgotten stents and failed stone retrieval were common following the procedure. The procedure of URS was simplified by the presence of dilated ureter in spontaneous stone passers or those with distal obstruction and proximal dilatation. It is concluded from the study that open surgery still remains the sheet anchor of treatment of urinary stones in many patients in Kerala. Newer lesser invasive procedures should be ethically selected. Decisions should be patient based, taking into consideration the economic feasibility for the procedure proposed.
本文试图评估喀拉拉邦地区现有尿路结石病治疗方式的当前状况。总共300名患有尿路结石病并通过不同方法取出结石的患者被选入该研究。对他们的临床症状、人口统计学特征、结石的大小、数量和位置、代谢指标、取出方式以及结石清除方面的治疗最终结果进行了评估。记录了失败、清除不完全和并发症事件的情况。基于这些经验,创建了一个流程图,用于尿路结石管理中的适当决策。取出方式包括肾切除术、肾切开取石术、肾盂肾切开取石术、扩大肾盂切开取石术、肾盂切开取石术、输尿管切开取石术、膀胱切开取石术、尿道切开取石术、体外冲击波碎石术(ESWL)、经皮肾镜取石术(PCNL)、输尿管镜检查(URS)、膀胱碎石术、尿道碎石术以及自然排出。开放手术的结石清除率最高。ESWL的结石清除程度取决于多种因素。PCNL大多受结石部位穿刺困难的限制。各种可弯曲肾镜的可用性也改变了该手术的成功率。将结石从输尿管推至肾盂后再进行PCNL有较好的成功率。在PCNL成功的患者中,就住院天数、恢复工作所需时间、无尿漏、手术部位感染、尿瘤形成和尿路感染而言,术后发病率显著降低。许多患者接受了URS并取出了结石。然而,该手术的适应症仍存疑问,因为如此取出的大多数结石尺寸小于6mm。这些结石可能会自然排出或在药物辅助下排出。URS、碎石术和套石术面临结石向上移入肾脏的问题,需要进一步的手术来取出。双J支架的引入有助于缓解尿路梗阻,特别是在无尿患者中,但术后支架留存、遗忘支架和结石取出失败的情况很常见。在自然排石者或存在远端梗阻和近端扩张的患者中,由于输尿管扩张,URS手术得以简化。该研究得出结论,在喀拉拉邦的许多患者中,开放手术仍然是尿路结石治疗的主要依靠。应从伦理角度选择创伤较小的新手术方法。决策应以患者为基础,考虑所提议手术的经济可行性。