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孕期体重过度增加的减少:一项随机对照试验。

Reducing excessive weight gain in pregnancy: a randomised controlled trial.

作者信息

Jeffries Kirby, Shub Alexis, Walker Susan P, Hiscock Richard, Permezel Michael

机构信息

Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, VIC, Australia.

出版信息

Med J Aust. 2009 Oct 19;191(8):429-33. doi: 10.5694/j.1326-5377.2009.tb02877.x.

DOI:10.5694/j.1326-5377.2009.tb02877.x
PMID:19835535
Abstract

OBJECTIVE

To determine if regular weight measurement throughout pregnancy can reduce excessive gestational weight gain.

DESIGN

A randomised controlled trial.

SETTING

A tertiary obstetric hospital in Melbourne, between July 2007 and May 2008.

PARTICIPANTS

236 pregnant women recruited at < or = 14 weeks' gestation.

INTERVENTION

Women allocated to the intervention group were given a personalised weight measurement card, advised of their optimal gestational weight gain (based on their body mass index at the time of recruitment and the United States Institute of Medicine guidelines), and instructed to record their weight at 16, 20, 24, 28, 30, 32 and 34 weeks' gestation. The control group were weighed at recruitment, but were not given instructions about regular weight measurement. All participants were blinded to the purpose of the study.

MAIN OUTCOME MEASURE

Weight gain from recruitment to follow-up at 36 weeks' gestation.

RESULTS

In the study population, there was a trend to less weight gain in the intervention group. The women in the intervention group experienced a mean (SD) per-week weight gain of 0.44 (0.173) kg compared with those in the control group, who gained 0.46 (0.156) kg/week (mean difference, 0.02 kg/week; 95% CI, - 0.02 to 0.07 kg/week). The intervention significantly reduced gestational weight gain in the group of women who were overweight but not obese at recruitment: those in the intervention group (20 women) gained a mean (SD) of 0.42 (0.153) kg/week and the control group (18 women) gained 0.54 (0.123) kg/week (mean difference, 0.12 kg/week; 95% CI, 0.03 to 0.22 kg/week; P = 0.01).

CONCLUSION

Regular weight measurement in pregnancy was not found to be effective in reducing weight gain, except among women who were overweight but not obese before pregnancy.

TRIAL REGISTRATION

Australian Clinical Trials Registry ACTRN12607000272493.

摘要

目的

确定孕期定期测量体重是否可减少孕期体重过度增加。

设计

一项随机对照试验。

地点

2007年7月至2008年5月期间,墨尔本一家三级产科医院。

参与者

招募了236名妊娠≤14周的孕妇。

干预措施

分配到干预组的女性会收到一张个性化体重测量卡,被告知其最佳孕期体重增加量(基于招募时的体重指数和美国医学研究所指南),并被要求记录其在妊娠16、20、24、28、30、32和34周时的体重。对照组在招募时称重,但未得到定期测量体重的指导。所有参与者对研究目的均不知情。

主要观察指标

从招募到妊娠36周随访期间的体重增加情况。

结果

在研究人群中,干预组体重增加有减少趋势。干预组女性每周平均(标准差)体重增加0.44(0.173)kg,而对照组女性每周体重增加0.46(0.156)kg(平均差异为0.02 kg/周;95%置信区间为-0.02至0.07 kg/周)。干预措施显著减少了招募时超重但不肥胖女性组的孕期体重增加:干预组(20名女性)每周平均(标准差)体重增加0.42(0.153)kg,对照组(18名女性)每周体重增加0.54(0.123)kg(平均差异为0.12 kg/周;95%置信区间为0.03至0.22 kg/周;P = 0.01)。

结论

未发现孕期定期测量体重对减少体重增加有效,除非是孕前超重但不肥胖的女性。

试验注册

澳大利亚临床试验注册中心ACTRN12607000272493。

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