Pasieka Janice L
Division of Surgical Oncology and General Surgery, Department of Surgery, University of Calgary, Calgary, AB T2N 2T0, Canada.
Surg Clin North Am. 2009 Oct;89(5):1123-37. doi: 10.1016/j.suc.2009.06.008.
Carcinoid tumors, which arise from the enterochromaffin cells of the gastrointestinal tract, encompass a diverse group of neoplasms. Once thought to be "carcinoma-like," these neoplasms exhibit a biologic behavior that varies from an indolent, benign course to an aggressive, rapidly progressive, and deadly disease. Today the term carcinoid is reserved for neuroendocrine tumors arising from the small bowel or neuroendocrine tumors that can cause carcinoid syndrome. This newer terminology has yet to be universally adopted, adding to the confusion in the literature. For the general surgeon there are several "carcinoid" tumors that he or she must be familiar with because many of these lesions are encountered during emergency laparotomies or incidentally discovered during investigation for vague abdominal pain. This review focuses on the gastrointestinal neuroendocrine tumors that general surgeons are likely to encounter during their career.
类癌肿瘤起源于胃肠道的肠嗜铬细胞，是一组多样的肿瘤。这些肿瘤曾被认为是“癌样的”，但其生物学行为差异很大，从惰性的良性病程到侵袭性、快速进展且致命的疾病都有。如今，类癌这一术语专指起源于小肠的神经内分泌肿瘤或可导致类癌综合征的神经内分泌肿瘤。这一新术语尚未被普遍采用，这也增加了文献中的混淆。对于普通外科医生来说，有几种“类癌”肿瘤是他们必须熟悉的，因为在急诊剖腹手术中会遇到许多这类病变，或者在对不明原因的腹痛进行检查时偶然发现。本综述聚焦于普通外科医生在职业生涯中可能遇到的胃肠道神经内分泌肿瘤。
