Peng Junjie, Lu Jiade, Xu Ye, Guan Zuqing, Wang Minghe, Cai Guoxiang, Cai Sanjun
Department of Colorectal Surgery, Cancer Hospital of Fudan University, Shanghai, China.
Am J Surg. 2010 Jun;199(6):753-8. doi: 10.1016/j.amjsurg.2009.03.026. Epub 2009 Oct 17.
Anastomotic leakage is a serious complication in rectal cancer surgery. More than one third of rectal cancer patients with low anterior resection (LAR) will receive defunctional stomas during primary operation.
Six hundred thirty-nine consecutive rectal cancer patients, whose tumors were located 5 to 12 cm from the anal verge, were treated with LAR. A standardized pelvic drainage for all these patients and selective irrigation for patients with leakage were conducted, and defunctional stoma was used as a salvage modality. All the anastomoses were all extraperitonealized during primary operations.
The anastomotic leakage rate was 7.04%. Male gender and location of tumor were found to be risk factors for leakage in patients with LAR. The overall stoma rate was 1.88%. Nearly 75% of leakage could be cured by irrigation-suction without surgical intervention. Severe complications, such as peritonitis, fistula, and obstruction, were strong predictors of irrigation failure.
Extraperitonealized anastomosis and pelvic drainage obtained a very low rate of defunctional stoma for LAR. Pelvic irrigation-suction was an effective modality to resolve anastomotic leakage.
吻合口漏是直肠癌手术中的一种严重并发症。超过三分之一的低位前切除术(LAR)直肠癌患者在初次手术期间将接受去功能化造口术。
对639例肿瘤位于距肛缘5至12厘米的连续性直肠癌患者进行了低位前切除术。对所有这些患者进行了标准化的盆腔引流,并对发生渗漏的患者进行了选择性冲洗,去功能化造口用作挽救措施。所有吻合口在初次手术期间均进行了腹膜外处理。
吻合口漏率为7.04%。发现男性和肿瘤位置是低位前切除术患者发生渗漏的危险因素。总体造口率为1.88%。近75%的渗漏可通过冲洗吸引治愈,无需手术干预。严重并发症,如腹膜炎、瘘管和梗阻,是冲洗失败的强烈预测因素。
腹膜外吻合和盆腔引流使低位前切除术的去功能化造口率非常低。盆腔冲洗吸引是解决吻合口漏的有效方式。